Improving literacy outcomes for all students requires educators to implement instructional practices that are compatible with how the brain learns. Neuroscience research has confirmed the efficacy of pedagogy that is both culturally responsive (Hammond, 2015) and rooted in the science of reading (Seidenberg, 2017) in developing the literacy proficiency of students in general education, students with learning differences, and culturally and linguistically diverse students. This session will provide educators across grade levels and content areas with frameworks and actionable best practices for building their own skills in both the science of reading and culturally responsive instruction. Using evidence-based instruction to strengthen our students’ reading and writing is a critical step we all can take for building a movement toward educational justice.